Brightons Trusted Chemical Peels Specialists
Why Mesoestetic® Chemical Peels Are a Core Part of Our Advanced Treatment Offering
Why Mesoestetic® Chemical Peels Are a Core Part of Our Advanced Treatment Offering
At Clinic 33, our approach is rooted in one core principle: evidence-led skincare tailored to the individual. We work with a carefully curated range of clinical-grade product lines—including Mesoestetic®, Medik8®, and Sesderma®—not out of brand loyalty, but because each offers unique strengths suited to different skin types, goals, and conditions.
When it comes to chemical peels, Mesoestetic® stands out as one of the most advanced tools in our professional toolkit—particularly for clients seeking deeper skin regeneration, treatment of pigmentation, or more complex conditions like melasma or acne scarring.
At A Glance
Duration of treatment:
60 Minutes
Mild – Moderate
– Pregnant or breastfeeding
– Have active skin infections (e.g., cold sores, acne flare-ups)
– Have used isotretinoin (Accutane) in the past 6–12 months
– Have certain skin conditions like eczema or psoriasis
– Have had recent facial surgery or radiation therapy
A consultation is required to ensure the treatment is right for you.
Depending on the peel’s depth, some redness or peeling may occur, typically resolving within a few days.
Clearer, smoother, and more even complexion. Continued improvement occurs over time as new skin cells regenerate and collagen builds.
while you may see noticeable improvement after just one session, a course of 3–6 treatments spaced 2–4 weeks apart is recommended for optimal, long-lasting results.
Chemical Peels, Many Options To Choose From, Why Mesoestetic?
Mesoestetic® chemical peels are formulated using pharmaceutical-grade actives and a multi-tiered approach to skin renewal, targeting both the epidermal and dermal layers with clinical precision. The science lies in their ability to safely trigger controlled cell turnover, while also modulating biochemical pathways responsible for pigmentation, inflammation, and ageing.
- Multi-Acid Synergy for Layered Penetration
Each peel uses a strategic combination of acids—such as glycolic, salicylic, lactic, mandelic, and trichloroacetic (TCA)—blended to act at specific depths within the skin:
- AHAs (Alpha Hydroxy Acids) loosen desmosomal bonds to exfoliate dead skin cells.
- BHAs (Beta Hydroxy Acids) penetrate oil glands, ideal for acne-prone skin.
- TCA targets dermal restructuring and collagen stimulation.
This synergistic layering enables results like pigment lifting, acne reduction, and fine line smoothing—all while reducing the risk of inflammation compared to single-acid peels.
- pH-Controlled Precision
The efficacy of a chemical peel isn’t just about acid percentage—it’s about pH and delivery control. Mesoestetic formulates its peels with precisely balanced pH levels that:
- Maximise penetration into targeted skin layers
- Minimise surface irritation
- Enhance bioavailability of active ingredients
This scientific control ensures deeper action with lower risk of barrier disruption or rebound hyperpigmentation.
- Cell Signalling and Melanocyte Modulation
Many Mesoestetic formulations are designed to modulate tyrosinase activity, which controls melanin production in the skin. This is especially relevant in treatments like:
- Cosmelan® – which downregulates pigment synthesis at the melanocyte level
- Mesopeel® Melanostop or Azelan – which inhibit inflammation-triggered pigmentation
The goal is not just to exfoliate pigment, but to correct the underlying biochemical dysfunction causing it.
- Dermal Stimulation & Fibroblast Activation
Stronger formulations (like modified Jessner or TCA peels) penetrate the reticular dermis and initiate a wound-healing cascade:
- Fibroblasts are activated to produce collagen and elastin
- Glycosaminoglycan production improves hydration and skin thickness
- Over time, this leads to improved skin density and elasticity
This makes Mesoestetic peels effective not just for surface rejuvenation, but for true anti-ageing treatment at a structural level.
- Nano-Encapsulation and Supportive Actives
Many Mesoestetic post-peel systems and supporting serums use nanotechnology delivery systems to drive antioxidants, peptides, and vitamins deeper into the skin post-treatment. This enhances:
- Recovery speed
- Barrier repair
- Continued results after peeling ends
Most Clinic’s Promote Their ‘Chemical Peels’ As The Best, Why Is This Different?
professional peels from Medik8® and Sesderma®—brands that shine in different areas such as sensitive skin, barrier repair, and gradual retexturing.
Each consultation begins with an in-depth skin analysis, allowing us to select the right tool for the job—whether that’s a gentler, enzyme-led peel, or a clinical-grade depigmentation system like Cosmelan®.
Mesoestetic is trusted in over 90 countries by dermatologists and advanced practitioners. Their flagship systems, such as:
– Cosmelan® (for pigmentation and melasma)
– Mesopeel® (for tailored exfoliation and restructuring)
…have earned a reputation as industry leaders for clinical-grade outcomes.
We use them not because of a brand allegiance, but because they consistently deliver measurable results in the right context.
We’re not here to “sell” you a brand. We’re here to understand your skin, your goals, and your lifestyle—and then guide you toward the best possible outcome using whatever combination of tools is most appropriate.
Sometimes that’s a Mesoestetic peel. Other times it’s Medik8’s gentle acids, or Sesderma’s nanotech formulations. The key is: we listen, then customise.
Our goal is not just good skin—but your best skin.
Book Your Professional Skin Consultation
If you’re considering a chemical peel in Brighton, Hove, or Sussex, book a free consultation with our expert team at Clinic 33. We’ll guide you through the options—without pressure or bias—so you feel informed, confident, and empowered about your skin journey.
Mesoestetic In a Nutshell?
Mesoestetic peels don’t just exfoliate—they communicate with the skin on a cellular level, triggering regeneration, regulating pigmentation, and restructuring collagen with medical precision.
They represent a fusion of cosmetic dermatology and pharmaceutical science, making them an essential tool for delivering predictable, long-term skin health improvements.
Treatment FAQ’s
Mesoestetic® peels are designed to target a wide range of concerns including acne, hyperpigmentation, fine lines, dullness, and uneven texture. Each peel is formulated to address specific skin issues, making it a highly customisable treatment option.
Yes, the Mesopeel® range includes formulations that are safe for most skin types, including sensitive and darker skin tones. Your practitioner will assess your skin during a consultation to ensure the right peel is selected for your individual needs.
Downtime depends on the strength of the peel used. Some clients experience mild redness or flaking for a few days, while others may have little to no visible peeling. You can usually return to normal activities straight after, though sun protection is essential.
Noticeable improvements can often be seen after just one session, but a course of 4–6 treatments spaced a few weeks apart is typically recommended for best results. This allows your skin to gradually renew and improve with each peel.
Mesoestetic® is a globally recognised medical aesthetics brand known for its scientific innovation and clinical-grade formulas. The Mesopeel® range is precision-engineered to be both effective and safe, offering targeted solutions with minimal disruption to your skin.
Absolutely. Mesoestetic® peels work well alongside treatments like microneedling, LED light therapy, or HydraFacial. Your practitioner can create a tailored treatment plan to maximise results based on your skin goals.